General Cell Based Assays
General Cell Based Assays
Thermo Scientific™ CellSensor™ TrkA-NFAT-bla CHO-K1 Cell Line
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
Thermo Scientific™ Kinase Tracer 236, 50 μM
In the LanthaScreen™ Eu Kinase Binding Assay, binding of an Alexa Fluor™ conjugate or tracer such as Kinase Tracer 236 to a kinase is detected by addition of a Eu-labeled anti-tag antibody.
Thermo Scientific™ Tango™ CNR2-bla U2OS Cells
The Tango™ CNR2-bla U2OS cells contain the human Cannabinoid Receptor 2 (CNR2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ CellSensor™ AP-1-bla A375 Cell Line
The CellSensor™ AP1-bla A375 cell line contains a beta-lactamase reporter gene under control of the AP1 response element stably integrated into A375 cells.
Thermo Scientific™ GeneBLAzer™ T-REx™-G2A-NFAT-bla FreeStyle™ 293F Cells
GeneBLAzer™ T-REx™ G2A-NFAT-bla Freestyle HEK 293F cells contain the human GPR132 (G2A), (Accession No. NP_037477) stably integrated into the CellSensor™ NFAT-bla Freestyle HEK 293F cell line.
Thermo Scientific™ GeneBLAzer™ GPR54-NFAT-bla CHO-K1 Cells
GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells contain the human KiSS1 receptor (GPR54) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ EDG4-bla U2OS Cells
The Tango™ EDG4-bla U2OS cells contain the human Endothelial Differentiation Gene 4 (EDG4) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ CellSensor™ SBE-bla A375 Cell Line
Bone morphogenetic proteins (BMPs), members of the transforming growth factor beta (TGF-β) superfamily, play important roles in the development of the heart, central nervous system and cartilage.
Thermo Scientific™ CellSensor™ IL1-bla ECV304 Cell Line
The CellSensor™ IL-1-bla ECV304 cell line is an adherent human urinary bladder cell line used to measure the (IL-1) signaling pathway via transcriptional regulation of the beta-lactamase gene.
Thermo Scientific™ GeneBLAzer™ EDG3-Gα15 HEK 293T DA Assay Kit
GeneBLAzer™ EDG3-Gα15 HEK 293T DA (Division Arrested) cells and EDG3-Gα15-NFAT-bla HEK 293T cells contain the human EDG3 receptor stably integrated in the GeneBLAzer™ Gα15-NFAT-bla HEK 293T cell line.
Thermo Scientific™ GeneBLAzer™ PTGDR CHO-K1 DA Assay Kit
GeneBLAzer™ PTGDR CHO-K1 DA (Division Arrested) cells and PTGDR-CRE-bla CHO-K1 cells contain the human Prostanoid (PTGDR) receptor stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ M4-Gqo5-NFAT-bla CHO-K1 Cells
GeneBLAzer™ M4 Gqo5-NFAT-bla CHO-K1 cells contain the human Acetylcholine (muscarinic) subtype 4 receptor (M4) stably integrated into the GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ M3-NFAT-bla CHO-K1 Cells
GeneBLAzer™ M3-NFAT-bla CHO-K1 cells contain the human Acetylcholine (Muscarinic) Receptor 3 (M3) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ Gα15-NFAT CHO-K1 DA Assay Kit
The GeneBLAzer™ Gα15-NFAT CHO-K1 DA (Division Arrested) cell line contains the promiscuous G protein, Gα15, stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ LanthaScreen™ TR-FRET Glucocorticoid Receptor Competitive Binding Kit
The LanthaScreen™ TR-FRET Glucocorticoid Receptor Competitive Binding Assay Kit provides a sensitive and robust method for high-throughput screening (HTS) of ligands for glucocorticoid receptor (GR).