Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

1 – 15 of 2,172 results

Thermo Scientific Chemicals Silver proteinate, mild, ∼20% silver

CAS: 1301199-90-5

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Specifications

CAS	1301199-90-5

Tocris Bioscience™ ProtiFect STAR™ Protein Transfection Reagent

Protein transfection reagent

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Invitrogen™ Bis-ANS (4,4'-Dianilino-1,1'-Binaphthyl-5,5'-Disulfonic Acid, Dipotassium Salt)

Binds with affinity that is often orders-of-magnitude higher than 1-8-ANS as probe for nonpolar cavities in proteins

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Invitrogen™ BODIPY™ 493/503 (4,4-Difluoro-1,3,5,7,8-Pentamethyl-4-Bora-3a,4a-Diaza-s-Indacene)

BODIPY™ 493/503 can be used as a stain for neutral lipds, and as a tracer for oil and other nonpolar lipids.

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Tocris Bioscience™ H 151

STING antagonist

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Specifications

Target	STING Antagonists
CAS	941987-60-6
Purity	98%
Chemical Name or Material	N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea
Recommended Storage	Store at 4°C
Synonym	ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173
Molecular Formula	C₁₇H₁₇N₃O
Formula Weight	279.34

Tocris Bioscience™ CMA

Murine-selective STING agonist

Pricing and Availability
Specifications

Target	STING Agonists
CAS	38609-97-1
Purity	98%
Chemical Name or Material	9-Oxo-10(9H)-acridineacetic acid
Recommended Storage	Store at 4°C
Synonym	ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173
Molecular Formula	C₁₅H₁₁NO₃
Formula Weight	253.25

Tocris Bioscience™ Ibrutinib

Potent and selective BTK inhibitor (IC50= 0.5 nM)

Pricing and Availability
Specifications

CAS	936563-96-1
Purity	98%
Chemical Name or Material	1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one
Recommended Storage	Store at -20°C
Synonym	Agammaglobulinaemia tyrosine kinase, AGMX1, ATKIMD1, B-cell progenitor kinase, BPK, Bruton agammaglobulinemia tyrosine kinase, Bruton tyrosine kinase, dominant-negative kinase-deficient Brutons tyrosine kinase, tyrosine-protein kinase
Molecular Formula	C₂₅H₂₄N₆O₂
Formula Weight	440.5

Invitrogen™ Ionomycin, Calcium Salt

Ionomycin is an effective Ca²⁺ ionopohre that is commonly used to both modify intracellular Ca²⁺ concentrations and to calibrate fluorescent Ca²⁺ indicators when studying the regulatory properties of Ca²⁺ in cellular processes.

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Molecular Probes™ Probenecid, Water Soluble

Probenecid, Water Soluble

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Guanidine Hydrochloride (Colorless-to-White Crystals), Fisher BioReagents™

For isolation of RNA from cell extracts

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Pricing and Availability
Specifications

CAS	50-01-1
Color	White
Purity	≥99.5%
Physical Form	Solid
Chemical Name or Material	Guanidine Hydrochloride
Recommended Storage	Store at Room Temperature
Synonym	guanidine hydrochloride
Merck Index	15, 4597
Molecular Formula	CH6ClN3
Formula Weight	95.53
Melting Point	178°C
Assay Percent Range	≥99.5%