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Thermo Scientific™ SMPT (4-succinimidyloxycarbonyl-alpha-methyl-α(2-pyridyldithio)toluene)

Crosslink amines to sulfhydryls with this crosslinker containing NHS-ester and pyridyldithiol groups at the ends of an aromatic, 6-atom (11.2A) spacer arm.

Brand:  Thermo Scientific™ 21558

Product Code. 11871235

  • 391.00 € / 50mg

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Description

Description

Thermo Scientific™ Pierce SMPT is a long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form strong (hindered) yet cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

Highlights:

  • Contains a hindered disulfide bond; forms stable immunotoxins
  • In vitro, an SMPT conjugate was as effective as conjugates formed with SPDP and 2-iminothiolane
  • Reactive groups: NHS ester and pyridyldisulfide
  • Reactive toward: amino and sulfhydryl groups
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Amine-Sulfhydryl
SMPT
No
Upon receipt store desiccated at 4°C.
Ambient
Chemical Labeling
NHS Ester, Pyridyldisulfide
Powder
DMF, DMSO
No
By Thiols
388.46
11.2 Å
Yes
Pierce™
Heterobifunctional
Medium (10 to 30 Å)
50 mg
Standard
Crosslinker
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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberXC319181 Certificate TypeCertificate of Analysis Date31/03/2022 Catalog Number21558
Lot NumberWC308683 Certificate TypeCertificate of Analysis Date14/04/2021 Catalog Number21558
Lot NumberVJ306587 Certificate TypeCertificate of Analysis Date27/10/2020 Catalog Number21558
Lot NumberVB299067 Certificate TypeCertificate of Analysis Date03/03/2020 Catalog Number21558
Lot NumberVA293506 Certificate TypeCertificate of Analysis Date18/01/2020 Catalog Number21558
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Thermo Scientific™ SMPT (4-succinimidyloxycarbonyl-alpha-methyl-α(2-pyridyldithio)toluene) > 50mg

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