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1 – 15 of 1,453 results
1

SB 431542, Tocris Bioscience™

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

Promotions are available
CAS 301836-41-9
Recommended Storage Store at Room Temperature
Molecular Formula C22H16N4O3
Formula Weight 384.39
2

Tocris Bioscience™ DFHBI 1T

Mimic of GFP fluorophore for imaging RNA in living cells

3

Tocris Bioscience™ RU.521

Potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS)

Promotions are available
Target Synthase/Synthetase Inhibitors
CAS 2262452-06-0
Purity 0.98
Chemical Name or Material 3-[1-(6,7-Dichloro-1 H-benzimidazol-2-yl)-5-hydroxy-3-methyl-1 H-pyrazol-4-yl]-1(3 H)-isobenzofuranone
Recommended Storage Store at -20°C
Molecular Formula C19H12Cl2N4O3
7

Tocris Bioscience™ BIRB 796

High affinity and selective p38 kinase inhibitor

Target p38 Inhibitors
CAS 285983-48-4
Purity 0.98
Chemical Name or Material N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N′-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea
Recommended Storage Store at -20°C
Synonym Doramapimod
Molecular Formula C31H37N5O3
Formula Weight 527.66
10

Tocris Bioscience™ MitoBrilliant 646

Universal red fluorescent mitochondrial stain for both live and fixed cells

Promotions are available
Target Mitochondria Dyes and Probes
Recommended Storage Store at -20°C
11

Tocris Bioscience™ 2-Phospho-L-ascorbic acid trisodium salt

Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs

12

Tocris™ ML 335

Selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activator

Product Type Activator
Purity 98%
Recommended Storage Store at 4°C
Molecular Formula C15H14Cl2N2O3S
Formula Weight 373.25
13

Tocris Bioscience™ JNJ 1013

Interleukin 1 Receptor Associated Kinase 1 (IRAK1) PROTAC™

14

TCS PIM-1 1, Tocris Bioscience™

CAS: 491871-58-0 Molecular Formula: C18H11BrN2O2 Molecular Weight (g/mol): 367.20 MDL Number: MFCD00276275 InChI Key: SVSYJTYGPLVUOZ-UHFFFAOYSA-N Synonym: tcs pim-1 1,6-5-bromo-2-hydroxyphenyl-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile,3-cyano-4-phenyl-6-3-bromo-6-hydroxy phenyl-2 1h-pyridone,6-5-bromo-2-hydroxyphenyl-2-oxo-4-phenyl-1h-pyridine-3-carbonitrile,2obj,pim1i,pyridone-based compound, 1,tcs pim-11,pim1-in-1 tcs pim-1 1,3-cyano-4-phenyl-6-3-bromo-6-hydroxyphenyl-2-pyridone PubChem CID: 1235170 ChEBI: CHEBI:86453 IUPAC Name: 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile SMILES: OC1=C(C=C(Br)C=C1)C1=CC(C2=CC=CC=C2)=C(C#N)C(=O)N1

PubChem CID 1235170
CAS 491871-58-0
Molecular Weight (g/mol) 367.20
ChEBI CHEBI:86453
MDL Number MFCD00276275
SMILES OC1=C(C=C(Br)C=C1)C1=CC(C2=CC=CC=C2)=C(C#N)C(=O)N1
Synonym tcs pim-1 1,6-5-bromo-2-hydroxyphenyl-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile,3-cyano-4-phenyl-6-3-bromo-6-hydroxy phenyl-2 1h-pyridone,6-5-bromo-2-hydroxyphenyl-2-oxo-4-phenyl-1h-pyridine-3-carbonitrile,2obj,pim1i,pyridone-based compound, 1,tcs pim-11,pim1-in-1 tcs pim-1 1,3-cyano-4-phenyl-6-3-bromo-6-hydroxyphenyl-2-pyridone
IUPAC Name 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile
InChI Key SVSYJTYGPLVUOZ-UHFFFAOYSA-N
Molecular Formula C18H11BrN2O2
15

GSK J4, Tocris Bioscience™

CAS: 1373423-53-0 Molecular Formula: C24H27N5O2 Molecular Weight (g/mol): 417.513 InChI Key: WBKCKEHGXNWYMO-UHFFFAOYSA-N Synonym: gsk-j4,gsk j4,ethyl 3-6-4,5-dihydro-1h-benzo d azepin-3 2h-yl-2-pyridin-2-yl pyrimidin-4-yl amino propanoate,ethyl 3-2-pyridin-2-yl-6-1,2,4,5-tetrahydro-3-benzazepin-3-yl pyrimidin-4-yl amino propanoate,gskj4,gsk-j hplc,ethyl 3-2-pyridin-2-yl-6-1,2,4,5-tetrahydro-3h-benzo d azepin-3-yl pyrimidin-4-yl amino propanoate,ethyl 3-2-pyridin-2-yl-6-2,3,4,5-tetrahydro-1h-3-benzazepin-3-yl pyrimidin-4-yl amino propanoate,n-2-2-pyridinyl-6-1,2,4,5-tetrahydro-3h-3-benzazepin-3-yl-4-pyrimidinyl-?-alanine ethyl ester,n-2-2-pyridinyl-6-1,2,4,5-tetrahydro-3h-3-benzazepin-3-yl-4-pyrimidinyl-beta-alanine ethyl ester PubChem CID: 71729975 IUPAC Name: ethyl 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate SMILES: CCOC(=O)CCNC1=NC(=NC(=C1)N2CCC3=CC=CC=C3CC2)C4=CC=CC=N4

PubChem CID 71729975
CAS 1373423-53-0
Molecular Weight (g/mol) 417.513
SMILES CCOC(=O)CCNC1=NC(=NC(=C1)N2CCC3=CC=CC=C3CC2)C4=CC=CC=N4
Synonym gsk-j4,gsk j4,ethyl 3-6-4,5-dihydro-1h-benzo d azepin-3 2h-yl-2-pyridin-2-yl pyrimidin-4-yl amino propanoate,ethyl 3-2-pyridin-2-yl-6-1,2,4,5-tetrahydro-3-benzazepin-3-yl pyrimidin-4-yl amino propanoate,gskj4,gsk-j hplc,ethyl 3-2-pyridin-2-yl-6-1,2,4,5-tetrahydro-3h-benzo d azepin-3-yl pyrimidin-4-yl amino propanoate,ethyl 3-2-pyridin-2-yl-6-2,3,4,5-tetrahydro-1h-3-benzazepin-3-yl pyrimidin-4-yl amino propanoate,n-2-2-pyridinyl-6-1,2,4,5-tetrahydro-3h-3-benzazepin-3-yl-4-pyrimidinyl-?-alanine ethyl ester,n-2-2-pyridinyl-6-1,2,4,5-tetrahydro-3h-3-benzazepin-3-yl-4-pyrimidinyl-beta-alanine ethyl ester
IUPAC Name ethyl 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate
InChI Key WBKCKEHGXNWYMO-UHFFFAOYSA-N
Molecular Formula C24H27N5O2