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Thermo Scientific™ DTME (dithiobismaleimidoethane)
Crosslink sulfhydryls to sulfhydryls (cysteine residues) with this long, cleavable crosslinker composed of maleimide groups and 11-atom (13.3A) disulfide spacer arm.
Brand: Thermo Scientific™ 22335
This item is not returnable.
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Description
Thermo Scientific™ Pierce DTME is a mid-length, maleimide crosslinker for reversible covalent conjugation between sulfhydryl groups (e.g., protein or peptide cysteines) by reduction of the disulfide bond in the center of the spacer arm.
Highlights:
- Cleavable by reducing agents
- Reactive groups: maleimide (homobifunctional)
- Reactive toward: sulfhydryl groups
Specifications
| Sulfhydryl-Sulfhydryl | |
| DTME | |
| No | |
| Upon receipt store desiccated at 4°C. | |
| Ambient | |
| Chemical Labeling | |
| Maleimide | |
| Solid | |
| DMF, DMSO | |
| No |
| By Thiols | |
| 312.36 | |
| 13.3 Å | |
| Yes | |
| Pierce™ | |
| Homobifunctional | |
| Medium (10 to 30 Å) | |
| 50 mg | |
| Standard | |
| Crosslinker |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- DTME (dithiobismaleimidoethane)
Signal Word
- Warning
Hazard Category
- Acute toxicity Category 4
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
Hazard Statement
- H302-Harmful if swallowed.
- H312-Harmful in contact with skin.
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H332-Harmful if inhaled.
- H335-May cause respiratory irritation.
Precautionary Statement
- P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P332+P313-If skin irritation occurs: Get medical advice/attention.
- P337+P313-If eye irritation persists: Get medical advice/attention.
Supplemental information
- MIXTURE LIST-Contains : Dithio-BisMaleimidoethane
For Research Use Only. Not for use in diagnostic procedures.